LC3 and p62 are widely used markers for understanding autophagy behavior in cells. The most reliable LC3 p62 interpretation comes from reading LC3-II and p62 together, considering timing, and accounting for whether the data reflect autophagic flux rather than steady-state accumulation. With those details in mind, these markers can provide meaningful insight into whether autophagy is functioning effectively or stalled at a step downstream of autophagosome formation.

28.03.2026. 22:03